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Murine Osteoblast to Osteocyte-like Cell Line

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Product Name

Murine Osteoblast to Osteocyte-like Cell Line

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Cat.No

ABI-TC037D

Species

Mouse

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Murine Osteoblast to Osteocyte-like cell line is a model for the osteoblast to osteocyte differentiation process, the mineralization process, and the effects of mechanical loading on biomineralization.Derived from a transgenic mouse in which the immortalizing T-antigen was expressed under control of the osteocalcin promoter.Osteocytes are the most abundant bone cells in the body but also the most challenging to study because they are embedded in a mineralized matrix making them to difficult to isolate. This cell line make it easier to study osteocyte function.

Disease

Normal

Source Organ

Kidney

Recommended Medium And Supplement
Citation Guide

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Application

For research use only

Morphology

Adherent osteoblast-like cell; honeycomb-like mineralized matrix within 7-9 days of culture

Immortalization Method

SV40 large T antigen

Growth Conditions

37 ℃, 5% CO2

Cell Type

Osteoblast

Growth Mode

Adherent

Product Type

Immortalized Cell Line

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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