Primary Cells

CD57 Mouse Cerebellar Astrocytes

  • For research use only

Cat No.

ABC-TC3317

Product Type

Mouse Primary Cells

Cell Type

Astrocyte

Species

CD57 Mouse

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Storage

Liquid Nitrogen

Astrocytes are the majority cell type of the mammalian brain.

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Description

CD57 Mouse Cerebellar Astrocytes are primary glial cells isolated from the cerebellar tissue of neonatal C57BL/6 mice. Cells are derived from healthy neonatal C57BL/6 mice with no known neurological abnormalities. These star-shaped cells represent a major component of the central nervous system (CNS) glia and are responsible for maintaining neuronal homeostasis, regulating synaptic transmission, and supporting the blood-brain barrier. After isolation, the astrocytes are cryopreserved at an early passage to preserve their native characteristics. Morphologically, they display a stellate appearance and grow as adherent monolayers in vitro. These cells do not proliferate indefinitely and cannot be passaged multiple times, so repeated freeze-thaw cycles should be avoided. C57BL/6 cerebellar astrocytes typically express GFAP (glial fibrillary acidic protein), S100β, and ALDH1L1. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

CD57 Mouse Cerebellar Astrocytes, Mouse Cerebellar Astrocytes, Cerebellar Astrocytes, Astrocytes, CAs, CD57 CAs

Species

CD57 Mouse

Cat.No

ABC-TC3317

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Astrocyte

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Brain

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Mouse Primary Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • CD57 Mouse Cerebellar Astrocytes provide a robust in vitro model for studying glial-neuronal interactions, neuroinflammation, and cerebellar development. These cells are particularly suitable for mechanistic studies of cerebellar neurodegenerative disorders such as spinocerebellar ataxia and multiple system atrophy. In neuroinflammation research, cerebellar astrocytes can be used to investigate the astrocytic response to cytokines, offering insights into the cellular crosstalk during cerebellar injury and neurodegeneration. These astrocytes also support metabolic studies of cerebellar glial energy regulation under oxidative or excitotoxic stress, as well as for studying CD57 mouse synaptic plasticity.

Citation

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