For research use only
| Cat No. | ABC-X0086C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Epithelial |
| Species | Crab-eating macaque |
| Host Cell | 293T |
| Source Organ | Kidney |
| Disease | Normal |
| Storage | Liquid Nitrogen |
The Cyno_DDR1 293T cell line provides a powerful tool for studying collagen signaling and drug responses, supporting research related to fibrosis.
Cyno_DDR1 293T Cell Line is a genetically engineered model derived from selected human 293T parental cell line based on customers’ requirement. Cynomolgus DDR1 overexpression cell line is generated by stable integration of exogenous cynomolgus monkey DDR1 gene into 293T host cells using our optimized transduction of lentiviral vectors.
Target
DDR1 (Discoidin Domain Receptor 1) encodes a receptor tyrosine kinase activated by collagen and is involved in cell adhesion, migration, and epithelial-mesenchymal transition. It is implicated in fibrosis and multiple cancers. Cynomolgus DDR1 shares high sequence identity with human DDR1, making it a suitable model for translational research. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Crab-eating macaque |
| Cat.No | ABC-X0086C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO₂ |
| Source Organ | Kidney |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | 293T |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Cyno_DDR1 293T Cell Line serves as a powerful tool for evaluating collagen receptor signaling, kinase inhibitor response, and cross-species therapeutic testing. This model enables comparative pharmacology and is suitable for preclinical antibody validation and fibrosis-related research.