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Cyno_FLT3 CHOK1 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Cyno_FLT3 CHOK1 Cell Line
Species

Crab-eating macaque
Cat.No

ABC-X0016C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Ovary
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

CHOK1

Description

Cyno_FLT3 CHOK1 Cell Line is a genetically engineered model derived from selected Chinese hamster ovary (CHOK1) parental cell line based on customers’ requirement. Cyno_FLT3 CHOK1 cell line is generated by stable integration of cynomolgus monkey FLT3 gene into CHOK1 host cells using our optimized transduction of lentiviral vectors.
Target
FLT3 encodes Fms-like tyrosine kinase 3, a receptor involved in hematopoietic stem cell proliferation and survival. In preclinical models, expression of cynomolgus FLT3 provides a relevant platform for studying cross-species receptor pharmacology and safety profiling. Cyno_FLT3-expressing cells are valuable in assessing the specificity and off-target effects of FLT3-targeting compounds in non-human primate systems. AcceGen offers generation of species-specific or customized gene expression cell lines. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • The Cyno_FLT3 CHOK1 Cell Line serves as a powerful tool to evaluate FLT3-targeted therapeutics in a cynomolgus background. This model enables preclinical testing for cross-reactivity, receptor activation, and kinase inhibition. It is utilized for safety assessment, pharmacodynamic analysis, and antibody-based screening during drug development.

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