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hESC/iPSC Y27632 Supplement

  • For research use only

Cat No.

ABC-CR007

Y27632 Supplement by AcceGen enhances hESC/iPSC survival by inhibiting ROCK and reducing apoptosis during culture, passaging, and cryopreservation.

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  • hESC/iPSC Y27632 Supplement
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Home | Cell Culture Media, kits & Reagents | Cell Culture Media & Reagents | hESC/iPSC Y27632 Supplement

Description

hESC/iPSC Y27632 Supplement is a selective, ATP-competitive inhibitor of ROCK-I and ROCK-II, specifically designed to enhance the survival and efficiency of human embryonic stem cells (hESCs) and induced pluripotent stem cells (iPSCs) during critical culture processes. By inhibiting Rho-associated kinase (ROCK) signaling pathway activation triggered by cell dissociation, it effectively reduces apoptosis and improves cell viability after passaging, freezing, and thawing. This supplement is essential for single-cell cloning, reaggregation culture, and enhancing attachment post-cryopreservation. It increases plating efficiency, supports clonal expansion, and improves overall culture robustness, making it a vital tool for regenerative medicine research, organoid development, and large-scale stem cell production.

Cat.No

ABC-CR007
Product Category

Cell Culture Media, kits & Reagents
Size/Quantity

1 kit
Shipping Info

Ice Pack
Storage

2-8°C

Application

  • The hESC/iPSC Y27632 Supplement is specifically formulated to significantly enhance the survival and cloning efficiency of human pluripotent stem cells during critical manipulation stages. It is essential for applications involving single-cell passaging, cryopreservation, thawing, and genetic modification of hESCs and iPSCs. By inhibiting ROCK-mediated apoptosis, this supplement reduces cell death and improves recovery after dissociation, supporting robust clonal expansion and high-density culture. It is widely used in regenerative medicine research, organoid formation, directed differentiation protocols, and large-scale production of clinically relevant stem cell lines. Its consistent performance helps maintain genomic stability and pluripotency in challenging culture conditions.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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