HighQC™ Human Amniotic Epithelial Stem Cell

Description

HighQC™ Human Amniotic Epithelial Stem Cells (HAESCs) are derived from the innermost epithelial layer of the amniotic membrane collected from full-term placentas. Cells exhibit adherent growth and form uniform monolayers with characteristic epithelial morphology in vitro. HAESCs are immunologically inert with low expression of major histocompatibility complex (MHC) class II antigens and demonstrate immune privilege, and possess the ability to differentiate into derivatives of all three germ layers, such as hepatocyte-like, neural, osteogenic, and pancreatic cells. In addition to epithelial markers like E‑cadherin and CK18, HAESCs express pluripotency‑associated transcription factors including OCT‑4, NANOG, and SOX‑2. They maintain a stable karyotype and exhibit no teratoma formation upon transplantation, reflecting their non‑tumorigenic phenotype. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.