HighQC™ Human Dental Pulp Stem Cell

Description

HighQC™ Human Dental Pulp Stem Cells (DPSCs) are mesenchymal stem cells derived from dental pulp tissue collected during routine dental procedures. They express CD105, CD90, and CD73, but not hematopoietic markers. They show spindle-shaped, fibroblast-like morphology and form CFU-F colonies under adherent conditions. They are non-tumorigenic with a normal karyotype. DPSCs can differentiate into odontoblasts, osteoblasts, neurons, adipocytes, and more. They are applicable to models of neurodegeneration, diabetes, myocardial infarction, spinal cord injury, and oral disease. In healthy tissue, they stay quiescent but can rapidly re-enter the cell cycle after injury. Their ability to generate neuron-like cells highlights potential in nerve regeneration and tissue engineering.

Application

• HighQC™ Human Dental Pulp Stem Cells (DPSCs)  have diverse applications in various fields. In toxicology and drug screening, DPSCs can be utilized as a reliable model for evaluating drug toxicity and screening potential therapeutic compounds.  In regenerative medicine, dentistry, and cell therapy, DPSCs show promise in tissue regeneration and repair, including dental tissue reconstruction. Additionally, DPSCs hold the potential for treating muscular dystrophy by differentiating into muscle cells and replacing damaged tissue. For corneal replacement treatment, DPSCs can be differentiated into corneal epithelial cells, providing a potential solution for corneal disorders. In the context of cardiovascular disease, DPSCs can be harnessed to generate cardiomyocytes for cardiac regeneration. Lastly, DPSCs contribute to comparative stem cell research, enabling scientists to study their unique properties and compare them with other stem cell types for a comprehensive understanding of stem cell biology.