HighQC™ Human Inferior Mesenteric Plexus Neuronal Stem Cell

Description

HighQC™ Human Inferior Mesenteric Plexus Neuronal Stem Cells (hIMPN‑SCs) are human enteric neuronal stem/progenitor cells derived from the autonomic nervous tissue of the inferior mesenteric plexus, a vital component of the enteric nervous system (ENS) responsible for regulating colonic motility and visceral reflexes. These cells are isolated from intestinal tissues, a method previously employed to obtain ENS progenitors in both developmental and disease-related contexts. hIMPN‑SCs display a bipolar or multipolar morphology and are cultured under defined, serum-free conditions that support neurosphere formation and maintain stemness. They express neural stem cell markers such as nestin and SOX2, commonly used to identify neural crest-derived enteric progenitors. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.