For research use only
| Cat No. | ABC-SC258Y |
| Product Type | Skeletal Myocytes |
| Cell Type | Muscle Cells |
| Species | Human |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skeletal Muscle |
| Disease | Duchenne Muscular Dystrophy |
| Storage | Liquid Nitrogen |
HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion models Duchenne muscular dystrophy for skeletal muscle disease and regenerative research.
HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion are human iPSC-derived skeletal myocytes generated from a human iPSC line originally derived from adult skin fibroblasts. These cryopreserved cells provide a defined in vitro model for Duchenne muscular dystrophy (DMD) research in skeletal muscle biology. The cells are produced through a directed differentiation protocol to support reproducible lineage-specific experimental systems. This line carries a deletion of exon 44 in the DMD gene, resulting in dystrophin deficiency relevant to Duchenne muscular dystrophy, without implying a fixed clinical phenotype. They retain skeletal muscle lineage characteristics relevant to myocyte research. Quality control testing includes sterility assessment and lineage characterization by protein expression and gene expression assays, where applicable. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.
| Product Code | Skeletal Myocytes DMD Exon 44 Delet n; HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Delet n; DMD |
| Species | Human |
| Cat.No | ABC-SC258Y |
| Product Category | Stem Cells |
| Size/Quantity | 1 vial |
| Cell Type | Muscle Cells |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Skeletal Muscle |
| Disease | Duchenne Muscular Dystrophy |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Skeletal Myocytes |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion are intended for research use in controlled in vitro workflows. They can be used for disease-relevant mechanism studies, genotype-associated pathway analysis, target validation, and candidate therapeutic evaluation in a human iPSC-derived skeletal myocytes model. As a dystrophin-null model, this line supports studies of dystrophin loss-of-function and myocyte membrane fragility relevant to Duchenne muscular dystrophy, at the mechanism and assay-development level, not clinical or diagnostic use.