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Stem Cells

HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion

  • For research use only

Cat No.

ABC-SC258Y

Product Type

Skeletal Myocytes

Cell Type

Muscle Cells

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Skeletal Muscle

Disease

Duchenne Muscular Dystrophy

Storage

Liquid Nitrogen

HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion models Duchenne muscular dystrophy for skeletal muscle disease and regenerative research.

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Description

HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion are human iPSC-derived skeletal myocytes generated from a human iPSC line originally derived from adult skin fibroblasts. These cryopreserved cells provide a defined in vitro model for Duchenne muscular dystrophy (DMD) research in skeletal muscle biology. The cells are produced through a directed differentiation protocol to support reproducible lineage-specific experimental systems. This line carries a deletion of exon 44 in the DMD gene, resulting in dystrophin deficiency relevant to Duchenne muscular dystrophy, without implying a fixed clinical phenotype. They retain skeletal muscle lineage characteristics relevant to myocyte research. Quality control testing includes sterility assessment and lineage characterization by protein expression and gene expression assays, where applicable. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Skeletal Myocytes DMD Exon 44 Delet n; HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Delet n; DMD

Species

Human

Cat.No

ABC-SC258Y

Product Category

Stem Cells

Size/Quantity

1 vial

Cell Type

Muscle Cells

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Skeletal Muscle

Disease

Duchenne Muscular Dystrophy

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Skeletal Myocytes

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HighQC Human iPSC-Derived Skeletal Myocytes DMD Exon 44 Deletion are intended for research use in controlled in vitro workflows. They can be used for disease-relevant mechanism studies, genotype-associated pathway analysis, target validation, and candidate therapeutic evaluation in a human iPSC-derived skeletal myocytes model. As a dystrophin-null model, this line supports studies of dystrophin loss-of-function and myocyte membrane fragility relevant to Duchenne muscular dystrophy, at the mechanism and assay-development level, not clinical or diagnostic use.

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