HighQC™ Human iPSC-Derived Ventricular Cardiomyocytes (Male)

Description

Human iPSC-Derived Ventricular Cardiomyocytes are generated from induced pluripotent stem cells, typically reprogrammed from somatic cells such as pulmonary fibroblasts (e.g., from a male donor). These cells express key cardiac markers, including ventricular-specific myosin heavy chain 7 (MYH7), cardiac troponin T (TNNT2), and troponin I (cTnI). Functionally, they display spontaneous beating, generate ventricular-like action potentials, and show excitation-contraction coupling, although with electrophysiological immaturity compared to adult cardiomyocytes. When combined with disease-specific interventions, these cells serve as models for studying cardiac pathologies such as arrhythmias, contractile dysfunction, or drug-induced cardiotoxicity.