HighQC™ Human IPSC From B-Lymphocyte(Facioscapulohumeral Muscular Dystrophy 1)

Description

HighQC™ Human Induced Pluripotent Stem Cells (iPSCs) From B Lymphocytes – Facioscapulohumeral Muscular Dystrophy Type 1 (FSHD1) are generated from human peripheral blood–derived B lymphocytes obtained from an affected individual. Facioscapulohumeral Muscular Dystrophy Type 1 is a heritable neuromuscular disorder. These cells display tight colony boundaries, high nuclear-to-cytoplasmic ratios, and clonal growth patterns. Reprogramming was performed using a non-integrating approach, which transiently expresses key human transcription factors to initiate the reprogramming process. These iPSCs exhibit pluripotency, with the ability to differentiate into types of all three germ layers under defined conditions, and express the pluripotency marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.