HighQC™ Human IPSC From Fibroblast-Choroideremia

Description

HighQC™ Human IPSC From Fibroblast-Choroideremia is a disease-specific human induced pluripotent stem cell line derived from dermal fibroblasts of a donor diagnosed with Choroideremia, an X-linked recessive chorioretinal dystrophy caused by mutations in the CHM gene. The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio. They maintain pluripotency and reflect CHM-related retinal traits. These cells retain the fundamental capacity for trilineage differentiation into cell types of the ectoderm, mesoderm, and endoderm germ layers. Core pluripotency marker SSEA-4 is expressed. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.