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HighQC™ Human IPSC From Fibroblast-Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types

  • For research use only

Cat No.

ABC-SC2040
Product Type

Human iPSCs
Cell Type

Induced Pluripotent Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Fibroblast
Disease

Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types
Storage

Liquid Nitrogen

HighQC™ Human IPSC From Fibroblast-Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types, ideal for disease modeling and therapeutic research.

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  • HighQC™ Human IPSC From Fibroblast-Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Induced Pluripotent Stem Cells (iPSCs) | HighQC™ Human IPSC From Fibroblast-Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types

Description

HighQC™ Human iPSCs From Fibroblasts–Epidermolysis Bullosa (Dystrophic, Junctional, or Simplex Types) are generated by reprogramming patient-derived dermal fibroblasts obtained from skin tissue. These cells originate from individuals affected by Epidermolysis Bullosa, a group of inherited skin fragility disorders encompassing dystrophic, junctional, or simplex subtypes. They exhibit classical human iPSC morphology, including compact colonies with well-defined borders, a high nucleus-to-cytoplasm ratio, and prominent nucleoli. These iPSCs exhibit pluripotency, with the ability to differentiate into all three germ layers under defined conditions, and express the pluripotency marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

HighQC™ Human IPSC From Fibroblast-Epidermolysis Bullosa, HighQC™ hiPSC EB, hiPSC-EB, HighQC™ Human Induced Pluripotent Stem Cells From Fibroblast-Epidermolysis Bullosa
Species

Human
Cat.No

ABC-SC2040
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Fibroblast
Disease

Epidermolysis Bullosa: Dystrophic, Junctional, Or Simplex Types
Storage

Liquid Nitrogen
Product Type

Human iPSCs

Application

  • HighQC™ Human iPSCs From Fibroblasts–Epidermolysis Bullosa (Dystrophic, Junctional, or Simplex Types), also known as Epidermolysis Bullosa iPSCs, provide a robust in vitro research model for investigating the molecular and cellular mechanisms underlying epidermal integrity and skin barrier formation, serving as an EB disease-in-a-dish model. These cells are widely used to study genotype–phenotype relationships associated with different Epidermolysis Bullosa subtypes, including defects in cell–cell and cell–extracellular matrix adhesion, cytoskeletal organization, and basement membrane assembly. Upon directed differentiation into keratinocytes or other skin-relevant lineages, they enable analysis of epidermal development, stratification, and differentiation under disease-relevant genetic backgrounds.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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