HighQC™ Human IPSC From Fibroblast-Long QT Syndrome 3

Description

HighQC™ Human IPSC From Fibroblast-Long QT Syndrome 3 is a disease-specific induced pluripotent stem cell line derived from dermal fibroblasts of a donor diagnosed with Long QT Syndrome Type 3 (LQT3), a cardiac arrhythmia disorder primarily caused by mutations in the SCN5A gene. The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio. The cells reflect LQT3 cardiac electrophysiology for mechanism research. They retain the fundamental capacity for trilineage differentiation into cell types representing the ectoderm, mesoderm, and endoderm germ layers under defined protocols. These cells express the core pluripotency marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.