HighQC™ Human IPSC From Fibroblast-Tuberous Sclerosis 2

Description

HighQC™ Human IPSC From Fibroblast-Tuberous Sclerosis 2 is a disease-specific human induced pluripotent stem cell line derived from dermal fibroblasts of a donor diagnosed with Tuberous Sclerosis Complex (TSC) Type 2, an autosomal dominant disorder caused by mutations in the TSC2 gene. The resulting iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio. They sustain pluripotency and reflect TSC2-related physiological traits. These cells retain the fundamental capacity for trilineage differentiation into ectoderm, mesoderm, and endoderm derivatives under directed conditions. They express core pluripotency marker SSEA-4. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.