HighQC™ Human IPSC From Limbal Epithelial Cells-Diabetes

Description

HighQC™ Human IPSC From Limbal Epithelial Cells-Diabetes is a disease-specific human induced pluripotent stem cell line derived from primary limbal epithelial cells, which were obtained from a donor with a clinical history of Diabetes Mellitus. The reprogramming was performed using non-integrating episomal plasmid method. The resulting human iPSCs (induced pluripotent stem cells) exhibit adherent growth with a high nucleus-to-cytoplasm ratio. The cells retain pluripotency for diabetic corneal physiological mechanism studies. They retain the fundamental capacity for trilineage differentiation into cell types of the ectoderm, mesoderm, and endoderm germ layers. Core pluripotency marker SSEA-4 is expressed. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.