HighQC™ Human IPSC From PBMC-Non-ALS MND

Description

HighQC™ Human IPSC From PBMC-Non-ALS MND is a disease-specific human induced pluripotent stem cell (iPSC) line derived from peripheral blood mononuclear cells (PBMCs) of a donor diagnosed with a non-amyotrophic lateral sclerosis motor neuron disease (Non-ALS MND). The reprogramming was performed using non-integrating episomal plasmid method. The resulting non-ALS MND iPSCs exhibit adherent growth with a high nucleus-to-cytoplasm ratio. They retain pluripotency for non-ALS MND mechanism exploration. These cells retain the fundamental capacity for trilineage differentiation into cell types of all three germ layers (ectoderm, mesoderm, and endoderm). Core pluripotency marker SSEA-4 is expressed. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.