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HighQC™ Human iPSC Line (Episomal, CB)

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Human iPSC Line (Episomal, CB) was derived from human new born cord blood (CB) mononuclear cells by ectopic expression of OCT4, SOX2, KLF4, L-MYC and Lin28 genes using episomal plasmids. The cells were derived using morphological selection criteria and without the use of fluorescent marker or drug selection.
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Primary Cells | HighQC™ Human iPSC Line (Episomal, CB)
Species

Human
Cat.No

ABC-SC003X
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human iPSCs

Description

HighQC™ Human iPSC Line (Episomal, CB)
The HighQC™ Human iPSC Line (Episomal, CB) is a human induced pluripotent stem cell line generated from cord blood mononuclear cells of a healthy newborn. Reprogramming of these cells was achieved using episomal plasmids expressing OCT4, SOX2, KLF4, L-MYC, and Lin28. The cells exhibit typical human embryonic stem cell morphology and they form compact colonies with a high nuclear-to-cytoplasmic ratio under standard ES cell culture conditions. These iPSCs retain a normal human karyotype, confirmed by G-banding, and are free from oncogenic mutations. They express key pluripotency markers including OCT4, SOX2, NANOG, SSEA-4, and TRA-1-60. These markers are essential for maintaining the pluripotent state of the cells and are commonly used to identify and characterize hiPSCs.

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Citation

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Application

  • In the study of disease mechanisms, HighQC™ Human iPSC Line (Episomal, CB) can be used to simulate the pathological process of genetic or acquired diseases by directing differentiation into specific cell types (such as neurons, cardiomyocytes or hepatocytes). In terms of drug screening and toxicity testing, its differentiated functional cells can be used for high-throughput drug evaluation to improve the accuracy and efficiency of preclinical research.

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