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HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells

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Human Peripheral Blood Mononuclear Cells (PBMC) are blood cells with a single round nucleus. These cells include lymphocytes (T, B and NK cells), monocytes and dendritic cells. Mononuclear cells are parts of the immune system which is critical for cell-mediated and humoral immunity. Mobilized peripheral blood is collected after the donor is treated with mobilization […]
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Home | Stem Cells | Adult Stem Cells | HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells
Species

Human
Cat.No

ABC-SC0088T
Product Category Stem Cells
Size/Quantity

1 vial
Cell Type

Monocyte
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Mobilized Peripheral Blood
Storage

Liquid Nitrogen
Product Type

Human Adult Stem Cells

Description

HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells are isolated from the peripheral blood of healthy donors after mobilization with cytokines (such as G-CSF). They mainly include lymphocytes (T/B/NK cells) and monocytest. As the core carrier of innate and adaptive immunity, T cells in PBMCs mediate cellular immunity, B cells produce antibodies, NK cells perform killing functions, and monocytes can differentiate into macrophages/dendritic cells to participate in antigen presentation. The dysfunction of these cells is associated with a variety of diseases: HIV infection leads to CD4+ T cell exhaustion and clonal lymphocyte proliferation in leukemia.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

  • HighQC™ Human Mobilized Peripheral Blood Mononuclear Cells can be used for in vitro functional evaluation of cell therapies such as CAR-T and TCR-T, as well as pharmacodynamic studies of checkpoint inhibitors (such as PD-1/PD-L1 antibodies). These cells can also be used to evaluate vaccine-induced T/B cell immune responses, including antigen-specific proliferation, cytokine secretion, and antibody production capacity.

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