HighQC™ Human Induced Pluripotent Stem Cells, From Schizophrenia

Description

HighQC™ Human Induced Pluripotent Stem Cells, From Schizophrenia, are derived from patients diagnosed with schizophrenia. These cells are generated using lentiviral vectors to deliver reprogramming factors to fibroblasts and are cultured under a feeder layer. These cells are generated by transducing four transcription factors, Oct3/4, Sox2, Klf4, and c-Myc, into skin fibroblasts using non-integrating methods. They express key pluripotency markers such as OCT4 and SSEA-4. These cells retain the full differentiation potential to generate all three germ layers — ectoderm, mesoderm, and endoderm — enabling the development of relevant neural cell types, including cortical neurons and glial cells. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.