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HighQC™ Human Induced Pluripotent Stem Cells, From Tay-sachs

  • For research use only

Cat No.

ABC-SC0229
Product Type

Human iPSCs
Cell Type

Induced Pluripotent Stem Cell
Species

Human
Growth Conditions

37 ℃, 5% CO2
Disease

Tay-sachs
Storage

Liquid Nitrogen

Heritable Diseases Lysosomal Storage Diseases;

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  • HighQC™ Human Induced Pluripotent Stem Cells, From Tay-sachs
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Home | Stem Cells | Induced Pluripotent Stem Cells (iPSCs) | Induced Pluripotent Stem Cells (iPSCs) | HighQC™ Human Induced Pluripotent Stem Cells, From Tay-sachs

Description

HighQC™ human induced pluripotent stem cells (iPSCs) from Tay-Sachs disease patients are derived from patient fibroblasts carrying disease-specific HEXA mutations. These cells exhibit classical pluripotent stem cell morphology. They are generated by transducing four transcription factors OCT4, SOX2, KLF4, and c-MYC into patient fibroblasts using Sendai virus. The expanded line was evaluated for viability surface antigen expression and alkaline phosphatase activity. Pluripotency was assessed via embryoid body (EB) formation. Each lot undergoes rigorous screening and isolation procedures, and is rigorously tested to ensure it is free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.

Product Code

HighQC™ Human Induced Pluripotent Stem Cells, From Tay-Sachs, Human iPSC-TaySachs, hIPSC-TS, Human Induced Pluripotent Stem Cells Tay-Sachs
Species

Human
Cat.No

ABC-SC0229
Product Category

Stem Cells
Size/Quantity

1 vial
Cell Type

Induced Pluripotent Stem Cell
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Disease

Tay-sachs
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Human iPSCs

Application

  • HighQC™ Human Induced Pluripotent Stem Cells, From Tay-sachs offer a powerful platform for disease modeling and drug discovery. Because these cells carry the patient-specific HEXA gene mutations responsible for Tay-Sachs disease, they enable researchers to study the molecular and cellular mechanisms underlying GM2 gangliosidosis in a human genetic context. They are also suitable for cytogenetic and genomic stability assessments, supporting disease-specific research and evaluation of therapeutic interventions.

Citation

When you publish your research, please cite our product as "AcceGen Biotech Cat.# XXX-0000". In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Frequently Asked Questions

  • What coating material and medium are recommended for culturing HighQC™ Induced Pluripotent Stem Cells, From Tay-Sachs?

    For culturing these cells, we recommend using Matrigel® as the coating material and mTeSR1™ as the culture medium.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
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