HighQC™ Porcine Bone Marrow Mesenchymal Stem Cell

Description

HighQC™ Porcine Bone Marrow Mesenchymal Stem Cells (pBM-MSCs) are primary mesenchymal stem cells isolated from the tibias and femurs of healthy female pigs via density-gradient centrifugation. These cells are derived from normal bone marrow. They are plastic-adherent and display a fibroblast-like, spindle-shaped morphology in vitro. pBM-MSCs are typically used at low passage numbers (<P5) to maintain multipotency. They express classical MSC markers such as wCD44 and CD90, but lack expression of the hematopoietic marker CD45. Immunohistochemistry confirms their differentiation capacity into osteogenic and adipogenic lineages. Calcium-binding proteins are upregulated during osteogenesis. Karyotype analysis has not been reported, and no viral contamination (e.g., PRRSV, PCV2) has been detected. These cells are non-tumorigenic and are commonly used in regenerative medicine, veterinary orthopedics, and stem cell therapy models involving bone and fat tissue repair.