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Primary Cells

HMVEC-d Neo Der MV Pooled Cells

  • For research use only

Cat No.

ABC-TC3466
Product Type

Dermal Cells
Cell Type

Endothelial
Species

Human
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Storage

Liquid Nitrogen

HMVEC-d Neo Der MV Pooled Cells provide a neonatal-derived dermal endothelial model for angiogenesis, vascular biology, and inflammation-related research.

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  • HMVEC-d Neo Der MV Pooled Cells
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Home | Primary Cells | Human Primary Cells | Others | HMVEC-d Neo Der MV Pooled Cells

Description

HMVEC-d Neo Der MV Pooled Cells are primary endothelial cells isolated from small vessels within skin tissue from either adults or neonatal foreskins. Cryopreserved after initial culture, these cells exhibit typical adherent growth and retain critical microvascular functions, including regulation of vascular permeability, angiogenesis, and leukocyte trafficking. They are implicated in diabetic microangiopathy, contributing to retinopathy/nephropathy, chronic inflammation driving psoriasis progression through endothelial activation, and impaired wound healing due to dysregulated VEGF signaling in hyperglycemia. Due to their sensitivity, repeated freezing and thawing should be avoided during culture. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

HMVEC-d Neonatal Dermal Microvascular Endothelial Cells Pooled, Neonatal Dermal MVECs Pool, HMVEC-d Neo Pooled Cells, Human Neonatal Skin MVECs Pooled, Dermal Microvascular ECs Neonatal Pool
Species

Human
Cat.No

ABC-TC3466
Product Category

Primary Cells
Size/Quantity

1 vial
Cell Type

Endothelial
Growth Mode

Adherent
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Dermal
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Dermal Cells
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • HMVEC-d Neo Der MV Pooled Cells serve as a standardized in vitro microvascular model to study the pathogenesis of diabetic dermal microangiopathy. Researchers can utilize them in investigating hyperglycemia-induced disruption of VE-cadherin junctions, leukocyte-endothelial adhesion cascades, and chronic inflammatory responses. Such studies reveal mechanisms of vascular leakage and chronic inflammation.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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