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| Product Code | huH-1; HUH-1; huH 1; HuH1; HUh1; HUH1; huH1 |
| Species | Human |
| Cat.No | ABC-TC0434 |
| Product Category | Tumor Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Epithelial-like |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 ℃, 5% CO2 |
| Source Organ | Liver |
| Disease | Hepatocellular Cancer |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Human Liver Cancer Cell Lines |
When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).
Huh-1 cell line is widely used to explore key signaling pathways in liver cancer, such as abnormal activation of Wnt/β-catenin, PI3K/AKT and MAPK pathways, and the effects of tumor suppressor gene (such as TP53) mutations on tumor progression. In addition, this cell line can be used to study the metastasis mechanism of liver cancer, especially the regulatory role of epithelial-mesenchymal transition (EMT) and angiogenesis-related factors.
huH-1 cells were originally isolated from liver of hepatocellular carcinoma, HBs-antigen carrier patient. Modal chromosome number is 69.
The culture medium recommended for huH-1 cells is composed of High Glucose DMEM supplemented with appropriate additives to support optimal cell growth and maintenance, add 10% FBS.
Hepatitis B virus (HBV) is detected in the huH-1 cell line with a high transcriptional activity. The huH-1 is one of the cell lines that used extensively to study HBV and carcinogenesis, as HBV integration is a risk factor that has been associated with HBV chronicity and hepatocellular carcinoma
