Primary Cells

Human Acute Myeloid Leukemia Bone Marrow Mononuclear Cells (Relapsed/Refractory)

  • For research use only

Cat No.

ABC-TC3018

Product Type

Immune Cells

Cell Type

Mononuclear Cell

Species

Human

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Acute Lymphoid Leukemia

Storage

Liquid Nitrogen

Bone Marrow is obtained from adult Acute Myeloid Leukemia patients.

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Description

Human Acute Myeloid Leukemia Bone Marrow Mononuclear Cells are isolated from adult acute myeloid leukemia (AML) patients in the relapsed/refractory stage. Bone marrow samples are diluted and centrifuged to obtain mononuclear cells, including leukemic blasts, lymphocytes, and monocytes. These primary, non-passaged cells exhibit irregular, blast-like morphology and are non-adherent. Functionally, they reflect advanced disease characteristics, supporting studies in resistance and hematopoietic dysregulation. Common markers include CD33, CD13, CD117, and HLA-DR. To ensure the quality of these primary cells, repeated freeze-thaw cycles are not recommended due to the fragile nature of these cells. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.

Product Code

Human Acute Myeloid Leukemia Bone Marrow Mononuclear Cells (Relapsed/Refractory), AML BM MNC R/R, Human AML BM MNC R/R

Species

Human

Cat.No

ABC-TC3018

Product Category

Primary Cells

Size/Quantity

1 vial

Cell Type

Mononuclear Cell

Growth Mode

Adherent

Shipping Info

Dry Ice

Growth Conditions

37 ℃, 5% CO2

Source Organ

Bone Marrow

Disease

Acute Lymphoid Leukemia

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Immune Cells

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • These cells are valuable for modeling chemoresistance mechanisms, tracking clonal evolution under therapeutic pressure, and analyzing immune interactions in the bone marrow niche. They support high-throughput drug screening, cytokine profiling, and functional genomics in relapsed acute myeloid leukemia (AML) contexts. Suitable for isolating subpopulations like CD34+ for studying stemness and differentiation blockade. They are also used to study therapy targets in refractory AML mononuclear and mononuclear cell changes in resistant leukemia, as well as hematopoietic dysregulation.

Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $200 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

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