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Transfected Stable Cell Lines

Human B2M_FCGRT 293T Cell Line

  • BSL

    1

  • 73
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human B2M_FCGRT 293T Cell Line
Species

Human
Cat.No

ABC-X0206C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Epithelial
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Kidney
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

293T

Description

The Human B2M_FCGRT 293T Cell Line was generated using lentiviral transduction technology to stably express the human B2M and FCGRT genes in 293T cells. 293T cells, derived from human embryonic kidney, are widely used in molecular biology research due to their high transfection efficiency and robust protein expression. Stable expression of B2M and FCGRT provides a reliable model for investigating IgG transport and recycling mechanisms.
Target
B2M (Beta-2-microglobulin) is a component of MHC class I molecules, involved in immune recognition. FCGRT (Fc fragment of IgG receptor and transporter) is critical for IgG homeostasis and transcytosis. Co-expression of B2M and FCGRT in this model enables evaluation of FcRn biology and therapeutic antibody pharmacokinetics. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line is ideal for in vitro studies of IgG half-life, FcRn-mediated IgG transport, antibody engineering, and immunotherapy development. It provides a powerful platform for pharmacodynamic studies and antibody recycling assays.

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