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Transfected Stable Cell Lines

Human B2M_HLA (A0201) K562 Cell Line

  • For research use only

Cat No.

ABC-X0369C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphoblast
Species

Human
Host Cell

K562
Source Organ

Bone Marrow
Disease

Chronic Myelogenous Leukemia
Storage

Liquid Nitrogen

Human B2M_HLA (A0201) K562 Cell Line, B2M, HLA, Overexpression Stable Cell Lines, Transfected Stable Cell Lines

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  • Human B2M_HLA (A0201) K562 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human B2M_HLA (A0201) K562 Cell Line

Description

Human B2M_HLA (A0201) K562 Cell Line is a genetically engineered model derived from selected human chronic myeloid leukemia K562 parental cell line based on customers’ requirement. B2M_HLA (A0201) K562 overexpression cell line is generated by stable integration of exogenous human B2M and HLA-A0201 genes into K562 host cells using our optimized transduction of lentiviral vectors. Overexpression clone is validated at gene level by qRT-PCR.
Target
B2M and HLA-A0201 constitute the major histocompatibility complex class I (MHC-I), crucial for antigen presentation and immune surveillance. Restoring MHC-I surface expression in immune-deficient K562 cells enables T-cell recognition studies. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0369C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphoblast
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Bone Marrow
Disease

Chronic Myelogenous Leukemia
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

K562
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The B2M_HLA (A0201) K562 Overexpression Cell Line is widely used in immunotherapy research, especially for T-cell receptor (TCR) specificity, peptide-MHC interaction, and cytotoxicity assays in engineered T-cell screening platforms.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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