For research use only
| Cat No. | ABC-X0052C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Lymphocytes |
| Species | Human |
| Host Cell | BAF3 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human BCR-ABL (A337T) BAF3 Cell Line provides a robust platform for exploring mutation-driven resistance to ABL inhibitors and leukemia progression.
The BCR_ABL (A337T) fusion gene encodes a mutant form of the BCR-ABL oncoprotein, in which alanine is replaced by threonine at position 337. This mutation can affect kinase activity or drug response and is relevant in studies of chronic myeloid leukemia (CML) and related disorders. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0052C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Lymphocytes |
| Growth Mode | Suspension |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Lymphatic |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | BAF3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
The Human BCR_ABL (A337T) BAF3 Cell Line is a valuable tool for studying oncogenic signaling pathways, drug resistance mechanisms in CML, and for evaluating the efficacy of kinase inhibitors targeting mutant BCR-ABL variants.