Transfected Stable Cell Lines

Human BCR _ABL (A337T) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0052C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

Human BCR-ABL (A337T) BAF3 Cell Line provides a robust platform for exploring mutation-driven resistance to ABL inhibitors and leukemia progression.

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Description

The BCR_ABL (A337T) fusion gene encodes a mutant form of the BCR-ABL oncoprotein, in which alanine is replaced by threonine at position 337. This mutation can affect kinase activity or drug response and is relevant in studies of chronic myeloid leukemia (CML) and related disorders. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0052C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The Human BCR_ABL (A337T) BAF3 Cell Line is a valuable tool for studying oncogenic signaling pathways, drug resistance mechanisms in CML, and for evaluating the efficacy of kinase inhibitors targeting mutant BCR-ABL variants.

Inquiring Human BCR _ABL (A337T) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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