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Transfected Stable Cell Lines

Human BCR_ABL (F359L) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0220C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human BCR_ABL (F359L) BAF3 Cell Line supports research on tyrosine kinase inhibitor resistance mechanisms in hematological malignancies.

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  • Human BCR_ABL (F359L) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BCR_ABL (F359L) BAF3 Cell Line

Description

The Human BCR_ABL (F359L) BAF3 Cell Line was constructed via lentiviral transduction to express the F359L-mutant BCR_ABL oncogene. The mutation supports IL-3-independent cell proliferation.
Target
F359L mutation reduces sensitivity to several TKIs by altering the kinase domain conformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0220C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Used to investigate resistance pathways and drug responsiveness in BCR_ABL-positive malignancies.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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