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Transfected Stable Cell Lines

Human BCR_ABL (F359L) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BCR_ABL (F359L) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0220C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

The Human BCR_ABL (F359L) BAF3 Cell Line was constructed via lentiviral transduction to express the F359L-mutant BCR_ABL oncogene. The mutation supports IL-3-independent cell proliferation.
Target
F359L mutation reduces sensitivity to several TKIs by altering the kinase domain conformation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Used to investigate resistance pathways and drug responsiveness in BCR_ABL-positive malignancies.

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