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Transfected Stable Cell Lines

Human BCR_ABL (M351T) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0224C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human BCR_ABL (M351T) BAF3 Cell Line serves as an effective model to study therapeutic resistance in BCR-ABL positive leukemia research.

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  • Human BCR_ABL (M351T) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BCR_ABL (M351T) BAF3 Cell Line

Description

The Human BCR_ABL (M351T) BAF3 Cell Line expresses the human BCR_ABL gene with the M351T mutation. The stable integration was achieved using lentiviral vectors, enabling IL-3-independent growth of BAF3 cells.
Target
M351T is a clinically relevant mutation that can moderately affect sensitivity to TKIs. It lies within the kinase domain of the ABL gene. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0224C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • Supports drug development and mutation profiling in BCR_ABL-driven leukemia research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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