Transfected Stable Cell Lines

Human BRAF (G464V) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0295C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

Human BRAF (G464V) BAF3 Cell Line enables detailed research on BRAF mutations involved in MAPK pathway dysregulation and therapy resistance.

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Description

Human BRAF (G464V) BAF3 Cell Line is derived from Ba/F3 cells through stable lentiviral integration of human BRAF carrying the G464V mutation. Expanded below passage 20, gene overexpression is confirmed by qRT-PCR.
Target
The G464V mutation enhances BRAF kinase activity and occurs in a subset of solid tumors, such as colorectal and thyroid cancer. It is associated with RAF dimerization and MEK-ERK hyperactivation. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0295C

Product Category

Transfected Stable Cell Lines

Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This model enables drug screening against non-V600 BRAF mutants and supports mechanistic studies of RAF dimer-targeted strategies.

Inquiring Human BRAF (G464V) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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