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Transfected Stable Cell Lines

Human BRAF (G466A) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0057C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocyte
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human BRAF (G466A) BAF3 cell line is designed for studying non-classical BRAF mutations and their roles in tumors, supporting drug development.

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  • Human BRAF (G466A) BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human BRAF (G466A) BAF3 Cell Line

Description

Human BRAF (G466A) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. The BRAF (G466A) mutant cell line is created by integrating the human BRAF gene with the G466A mutation into Ba/F3 cells using optimized lentiviral transduction.
Target
BRAF is a serine/threonine kinase functioning within the MAPK pathway. The G466A mutation is located in the kinase domain and results in deregulated kinase activity and ERK pathway hyperactivation. It is associated with non-V600E driven malignancies including melanoma and NSCLC. AcceGen offers precise BRAF mutation models for functional validation and drug discovery. Polyclonal or monoclonal is optional.

Species

Human
Cat.No

ABC-X0057C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The BRAF (G466A) BAF3 Cell Line enables exploration of non-canonical BRAF-driven oncogenic mechanisms, targeted drug response, and resistance development. It is an ideal system for preclinical screening and personalized medicine research.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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