Human Bronchial Smooth Muscle Cells

Description

Human Bronchial Smooth Muscle Cells (HBSMC) are isolated from human bronchial and bronchiolar tissues. These cells are cryopreserved at early passage and play a crucial role in regulating airway tone by contracting and relaxing to control airflow, and are directly involved in the pathophysiology of various respiratory diseases, including asthma and chronic obstructive pulmonary disease (COPD). HBSMCs are also key contributors to airway remodeling and inflammation through their interaction with immune mediators and extracellular matrix components. They express smooth muscle actin and vimentin. The cells undergo rigorous screening and isolation procedures, and are rigorously tested to ensure they are free of contamination from HIV-1, HBV, HCV, syphilis, mycoplasma, fungi, yeast, and bacteria.