+1 862-686-2696

  • Buy 1 Get 1 FREE for immortalized cells| limited time until end of June

  • Boost Your Research with FREE Freezing Medium

Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, Kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human cKIT (V559D_D820G) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0054C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocyte
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human cKIT (V559D_D820G) BAF3 cell line is an ideal model for researching GIST and hematologic malignancies, supporting compound screening.

Product Image
  • Human cKIT (V559D_D820G) BAF3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human cKIT (V559D_D820G) BAF3 Cell Line

Description

Human cKIT (V559D_D820G) BAF3 Cell Line is a genetically engineered model derived from selected murine Ba/F3 parental cell line based on customers’ requirement. This dual mutant model is constructed by lentiviral integration of human cKIT gene harboring V559D and D820G mutations.
Target
cKIT is a receptor tyrosine kinase that regulates hematopoiesis, melanogenesis, and gametogenesis. The V559D mutation leads to constitutive activation in the juxtamembrane domain, while D820G, in the kinase domain, is associated with secondary resistance to cKIT inhibitors. This dual mutant enables in-depth analysis of cKIT signaling dysregulation and drug resistance. AcceGen supports generation of dual or complex mutation models to meet custom research needs. Polyclonal or monoclonal is optional.

Species

Human
Cat.No

ABC-X0054C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocyte
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO₂
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • The cKIT (V559D_D820G) BAF3 Cell Line is ideal for studying oncogenic signaling, drug resistance mechanisms, and combination therapy testing in GIST and hematologic malignancies. It enables high-throughput compound screening and precision oncology development.

  • Online Inquiry
  • Product Reviews

Inquiring Human cKIT (V559D_D820G) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button