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Human CLIP1_LTK (F568C) NIH/3T3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (F568C) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0301C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human CLIP1_LTK (F568C) NIH/3T3 Cell Line is a murine fibroblast cell line stably expressing the human CLIP1_LTK fusion with the F568C mutation. NIH/3T3 cells are frequently used in oncogene transformation assays, and this model is specifically designed to assess the oncogenic potential of mutant LTK fusions in solid tumors.
Target
The CLIP1_LTK fusion involves the linkage of the CLIP1 promoter to the LTK (leukocyte tyrosine kinase) kinase domain, a known oncogenic driver in lung and other cancers. The F568C substitution within the kinase domain may enhance constitutive signaling and oncogenic activity.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell model is ideal for investigating the signaling mechanisms of CLIP1_LTK F568C, evaluating LTK inhibitors, and conducting preclinical drug efficacy studies. It supports exploration of resistance mechanisms and development of personalized medicine strategies.

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