For research use only
| Cat No. | ABC-X0304C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Host Cell | NIH/3T3 |
| Source Organ | Embryo |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human CLIP1_LTK (G663A) NIH/3T3 Cell Line enables functional studies on CLIP1_LTK-driven tumorigenesis and the evaluation of selective kinase inhibitors.
Human CLIP1_LTK (G663A) NIH/3T3 Cell Line is a genetically modified fibroblast line expressing the CLIP1_LTK fusion gene harboring the G663A mutation. It is designed to explore the biological relevance of kinase domain variants in oncogenic signaling.
Target
G663A lies in the kinase domain of LTK and may affect ATP binding or kinase activity. The mutation is of interest for understanding how specific alterations contribute to tumor progression or therapeutic resistance.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0304C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NIH/3T3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This model is applicable to studying mutation-specific pathway activation, drug response profiling, and elucidating molecular mechanisms of LTK-driven transformation.