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Human CLIP1_LTK (I565N) NIH/3T3 Cell Line

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  • 92
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (I565N) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0305C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human CLIP1_LTK (I565N) NIH/3T3 Cell Line is a stable fibroblast line expressing the CLIP1_LTK fusion with an I565N point mutation. This model facilitates the study of mutation-specific oncogenicity and LTK-targeted therapies in vitro.
Target
I565N is a substitution mutation within the kinase domain of LTK, potentially modulating its catalytic activity or altering downstream signaling. It has been associated with aberrant proliferation and tumorigenesis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line is ideal for drug screening, pathway dissection, and evaluating resistance mechanisms associated with I565N in the CLIP1_LTK fusion context.

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