For research use only
| Cat No. | ABC-X0305C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Host Cell | NIH/3T3 |
| Source Organ | Embryo |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human CLIP1_LTK (I565N) NIH/3T3 Cell Line is designed to investigate CLIP1_LTK mutation effects on cell signaling and anti-cancer drug sensitivity.
Human CLIP1_LTK (I565N) NIH/3T3 Cell Line is a stable fibroblast line expressing the CLIP1_LTK fusion with an I565N point mutation. This model facilitates the study of mutation-specific oncogenicity and LTK-targeted therapies in vitro.
Target
I565N is a substitution mutation within the kinase domain of LTK, potentially modulating its catalytic activity or altering downstream signaling. It has been associated with aberrant proliferation and tumorigenesis. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0305C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NIH/3T3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
This cell line is ideal for drug screening, pathway dissection, and evaluating resistance mechanisms associated with I565N in the CLIP1_LTK fusion context.