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Human CLIP1_LTK (L590M) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (L590M) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0290C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human CLIP1_LTK (L590M) BAF3 Cell Line is a Ba/F3-derived model stably expressing the CLIP1-LTK fusion with the L590M mutation, generated by lentiviral transduction. Expanded under low passage conditions, gene expression is confirmed by qRT-PCR.
Target
The L590M mutation resides within the LTK kinase domain and is associated with enhanced kinase function and oncogenic potential. CLIP1-LTK fusions are emerging targets in fusion-driven cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model supports discovery and validation of small molecule inhibitors against LTK fusions and resistance variants.

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