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Human CLIP1_LTK (L590M) NIH/3T3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (L590M) NIH/3T3 Cell Line
Species

Human
Cat.No

ABC-X0302C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Embryo
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

NIH/3T3

Description

Human CLIP1_LTK (L590M) NIH/3T3 Cell Line is engineered to express the CLIP1_LTK fusion protein with an L590M mutation in NIH/3T3 cells. This model allows for the study of gain-of-function effects and pathway alterations induced by this specific mutation in fibroblast cells.
Target
The L590M mutation occurs within the LTK tyrosine kinase domain and is hypothesized to enhance kinase activity or alter inhibitor binding. It is relevant to targeted cancer therapy research and understanding mutation-specific signaling profiles.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line provides a valuable platform for studying CLIP1_LTK-driven tumorigenesis, screening small-molecule inhibitors, and analyzing downstream signaling cascades activated by the L590M variant.

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