For research use only
| Cat No. | ABC-X0306C |
| Product Type | Overexpression Stable Cell Lines |
| Cell Type | Fibroblast |
| Species | Human |
| Host Cell | NIH/3T3 |
| Source Organ | Embryo |
| Disease | Normal |
| Storage | Liquid Nitrogen |
Human CLIP1_LTK (L592F) NIH/3T3 Cell Line serves as a valuable model to study CLIP1_LTK fusion-driven oncogenesis and drug discovery in solid tumors.
Human CLIP1_LTK (L592F) NIH/3T3 Cell Line expresses the CLIP1_LTK fusion gene with an L592F mutation in NIH/3T3 cells, offering a powerful tool to investigate the transformation potential of this variant in a fibroblast background.
Target
The L592F mutation within the LTK kinase domain is thought to enhance kinase activation and may contribute to neoplastic signaling. Understanding its biological role is essential for developing LTK-specific inhibitors.
AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
| Species | Human |
| Cat.No | ABC-X0306C |
| Product Category | Transfected Stable Cell Lines |
| Size/Quantity | 1 vial |
| Cell Type | Fibroblast |
| Growth Mode | Adherent |
| Shipping Info | Dry Ice |
| Growth Conditions | 37 °C, 5% CO2 |
| Source Organ | Embryo |
| Disease | Normal |
| Biosafety Level | 1 |
| Storage | Liquid Nitrogen |
| Product Type | Overexpression Stable Cell Lines |
| Host Cell | NIH/3T3 |
| Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Useful for tumorigenesis modeling, this cell line supports drug testing and mechanistic studies involving the CLIP1_LTK L592F variant.