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Human CLIP1_LTK (L650F) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human CLIP1_LTK (L650F) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0340C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human CLIP1_LTK (L650F) BAF3 Overexpression Cell Line is a genetically engineered Ba/F3 model expressing the CLIP1-LTK fusion harboring the L650F mutation. The gene is stably integrated using lentiviral vectors, and expression is validated via qRT-PCR. Cells are maintained below passage 20.
Target
CLIP1_LTK fusion activates LTK kinase signaling, and the L650F mutation enhances kinase activity, driving oncogenesis in certain non-small cell lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line facilitates preclinical assessment of LTK-targeted therapies and supports research into resistance mechanisms associated with LTK mutations.

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