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Transfected Stable Cell Lines

Human CLIP1_LTK (L650F) BAF3 Cell Line

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Species

Human

Cat.No

ABC-X0340C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Description

Human CLIP1_LTK (L650F) BAF3 Overexpression Cell Line is a genetically engineered Ba/F3 model expressing the CLIP1-LTK fusion harboring the L650F mutation. The gene is stably integrated using lentiviral vectors, and expression is validated via qRT-PCR. Cells are maintained below passage 20.
Target
CLIP1_LTK fusion activates LTK kinase signaling, and the L650F mutation enhances kinase activity, driving oncogenesis in certain non-small cell lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

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Application

  • For research use only

  • This cell line facilitates preclinical assessment of LTK-targeted therapies and supports research into resistance mechanisms associated with LTK mutations.

Inquiring Human CLIP1_LTK (L650F) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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