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Species | Human |
Cat.No | ABC-X0340C |
Quality Control | All cells test negative for mycoplasma, bacteria, yeast, and fungi. |
Product Category | Transfected Stable Cell Lines |
Size/Quantity | 1 vial |
Cell Type | Lymphocytes |
Shipping Info | Dry Ice |
Growth Conditions | 37 °C, 5% CO2 |
Source Organ | Lymphatic |
Disease | Normal |
Biosafety Level | 1 |
Storage | Liquid Nitrogen |
Product Type | Overexpression Stable Cell Lines |
Host Cell | BAF3 |
Human CLIP1_LTK (L650F) BAF3 Overexpression Cell Line is a genetically engineered Ba/F3 model expressing the CLIP1-LTK fusion harboring the L650F mutation. The gene is stably integrated using lentiviral vectors, and expression is validated via qRT-PCR. Cells are maintained below passage 20.
Target
CLIP1_LTK fusion activates LTK kinase signaling, and the L650F mutation enhances kinase activity, driving oncogenesis in certain non-small cell lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.
For research use only