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Transfected Stable Cell Lines

Human CLIP1_LTK (L650F) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0340C

Product Type

Overexpression Stable Cell Lines

Cell Type

Lymphocytes

Species

Human

Host Cell

BAF3

Source Organ

Lymphatic

Disease

Normal

Storage

Liquid Nitrogen

Human CLIP1_LTK (L650F) BAF3 Cell Line serves as a model to explore CLIP1-LTK fusion variant-induced tumor signaling and small molecule inhibition.

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Description

Human CLIP1_LTK (L650F) BAF3 Overexpression Cell Line is a genetically engineered Ba/F3 model expressing the CLIP1-LTK fusion harboring the L650F mutation. The gene is stably integrated using lentiviral vectors, and expression is validated via qRT-PCR. Cells are maintained below passage 20.
Target
CLIP1_LTK fusion activates LTK kinase signaling, and the L650F mutation enhances kinase activity, driving oncogenesis in certain non-small cell lung cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human

Cat.No

ABC-X0340C

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial

Cell Type

Lymphocytes

Growth Mode

Suspension

Shipping Info

Dry Ice

Growth Conditions

37 °C, 5% CO2

Source Organ

Lymphatic

Disease

Normal

Biosafety Level

1

Storage

Liquid Nitrogen

Product Type

Overexpression Stable Cell Lines

Host Cell

BAF3

Application

  • For research use only

  • This cell line facilitates preclinical assessment of LTK-targeted therapies and supports research into resistance mechanisms associated with LTK mutations.

Inquiring Human CLIP1_LTK (L650F) BAF3 Cell Line

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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