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Human Colonic Epithelial Cells

Product Name

Human Colonic Epithelial Cells

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Product Code

HCoEpiC

Cat.No

ABC-TC3570

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Colonic epithelium cover the colonic mucosal surface and maintain the gut homeostasis by harboring the commensal bacteria in the outer mucus layer. Most colonic epithelial cells are absorptive colonocytes distributed in the crypt top, composed of specilised lineages including secretory goblet and enteroendocrine cells (EECs). They not only coordinate gut absorptive and secretory process, but also control mucosal immunity by presenting antigens to T cells. Dysregulation of the colonic homeostasis is often associated with intestinal inflammation, which underpins various intestinal disorders including bacterial infection, inflammatory bowel disease (IBD) and colonic cancer.
Why choose Human Colonic Epithelial Cells from AcceGen?
AcceGen human colonic epithelial cells are isolated from human colon tissue. Cells at P1 are cryopreserved immediately after isolation. Each vial contains more than 5×10^5 cells in 1 ml volume. Cells are characterized positive for CK18 and CK19 by immunofluorescence. All cell lots are tested negative for HIV-1, HBV, HCV and other pathogens. Human colonic epithelial cells are quality tested to further culture for 10 population doublings following AcceGen’s recommended protocols.

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only
Human colonic epithelial cells provide an ideal cell culture model for studying the physiology and pathophysiology of epithelial cells, including:
-Colonic signalling pathways associated with colonic inflammation and carcinogenesis such as TGF-β and Gpr109a receptor
-Drug and Zinc oxide nanoparticles safety evaluation
-Genetic expression profiling
-Host-microorganism symbiosis and their instructive role in mucosal immunity
-Electrocyte transportation of colon epithelium and their potential role in disease

Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results
-Expert teams to provide timely support and assist best experimental outcomes

Product Type

Intestinal Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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