+1 862-686-2696
Featured Products
Primary Cells
Immortalized Cell Lines
Stem Cells
Tumor Cell Lines
Transfected Stable Cell Lines
Exosomes
MicroRNA Agomir/Antagomir
Cell Culture Media, kits & Reagents
Explore Products
Cell
Cell
MicroRNA
MicroRNA
Test and Analysis
Test and Analysis
Transfected Stable Cell Lines

Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0288C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line enables research on oncogenic ALK fusion variants and their roles in tumor progression and therapy.

Product Image
  • Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line
Get a Quote
Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line

Description

Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line is a murine Ba/F3-derived model expressing the EML4-ALK fusion gene with F1174C and G1202R mutations. The model is established by lentiviral delivery and maintained below passage 20. Gene expression is verified by qRT-PCR.
Target
EML4-ALK fusions drive oncogenesis via constitutive ALK kinase activity. F1174C and G1202R variants promote enhanced signaling and drug resistance. This double mutant is of high relevance in relapsed ALK-positive cancers. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

Species

Human
Cat.No

ABC-X0288C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This dual-mutant fusion model enables exploration of compound mutation effects in ALK signaling and development of advanced targeted inhibitors.

  • Online Inquiry
  • Product Reviews

Inquiring Human EML4_ALK (F1174C_G1202R) BAF3 Cell Line

We know how valuable your research is to you, but are you wondering what you can expect to pay for quick accurate results every time? Fill out a request in the form below and we’ll get back to you within 24 hours with a quote.
High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

Tags

Let's Advance Life Science Research Together

Contact Us
AcceGen Scroll Top Button