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Human EML4_ALK (R1275Q) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human EML4_ALK (R1275Q) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0093C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human EML4_ALK (R1275Q) BAF3 Cell Line is a stable murine pro-B cell model derived from Ba/F3 cells, engineered via lentiviral transduction to express the EML4-ALK fusion gene with a clinically significant R1275Q mutation. Transgene expression is verified by qRT-PCR, and the cells are maintained at low passage numbers (

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This model enables functional characterization of EML4-ALK fusion activity and resistance mechanisms to ALK-targeted therapies, serving as a preclinical tool for drug screening and biomarker validation.

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