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Transfected Stable Cell Lines

Human ERBB4 (G776S) BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human ERBB4 (G776S) BAF3 Cell Line
Species

Human
Cat.No

ABC-X0422C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human ERBB4 (G776S) BAF3 Cell Line is a genetically modified Ba/F3 cell line expressing the G776S-mutant form of human ERBB4. This model enables the analysis of functional consequences of the G776S substitution.
Target
The G776S mutation enhances ERBB4 kinase activity and contributes to tumorigenic signaling. It has been identified in several cancers and linked to therapeutic resistance. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers’ research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • Useful for studying oncogenic ERBB4 variants and testing inhibitors that target activated ERBB4 signaling.

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