Human Esophageal Microvascular Endothelial Cells

Description

Human Esophageal Microvascular Endothelial Cells (HEMEC) are adherent, cobblestone-appearing cells isolated from normal human esophageal tissue obtained from healthy donors. As endothelial cells of the esophageal microvasculature, they function as critical gatekeepers in inflammation by regulating leukocyte adhesion and transmigration through expression of adhesion molecules (e.g., ICAM-1, VCAM-1, E-selectin) in response to inflammatory cytokines. HEMEC maintain endothelial marker expression, including CD31, VE-cadherin, and von Willebrand factor (vWF), confirming their identity and vessel-specific function. Their stable morphology and functional responsiveness make HEMEC a reliable model for esophageal microvascular biology, inflammation, angiogenesis, and immune cell trafficking research. Each lot undergoes rigorous screening and isolation procedures and is tested to ensure it is free from contamination by HIV-1, HBV, HCV, Syphilis, Mycoplasma, Fungi, Yeast, and Bacteria.