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Human Esophageal Smooth Muscle Cells

Product Name

Human Esophageal Smooth Muscle Cells

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Product Code

HESMC

Cat.No

ABC-TC3615

Species

Human

Size/Quantity

1 vial

Biosafety Level

1

Shipping Info

Dry Ice

Storage

Liquid Nitrogen

Description

Smooth muscle is responsible for the contractility of hollow organs, such as blood vessels, the gastrointestinal tract, the bladder, and the uterus. Its structure differs greatly from that of skeletal muscle. The human esophagus contains three layers of muscle in its walls, the outer longitudinal and inner circular layers of the main muscular coat and the muscular layer of the mucosa. Visceral smooth muscle cells makes up all three layers along the entire organ except for the most rostral few centimeters. Smooth muscle contraction is critical to peristalsis in the human esophagus and the contraction may be mediated by activation of phospholipase through two distinct mechanisms (increased intracellular Ca2+ and G protein activation) and activating PKCepsilon-dependent mechanisms. In vitro study also shows that cultured human esophageal smooth muscle cells express voltage-dependent Na(+) channels.HESMC from AcceGen Research Laboratories are isolated from the human esophagus. HESMC are cryopreserved at secondary culture and delivered frozen. Each vial contains >5×10^5 cells in 1 ml volume. HESMC are characterized by immunofluorescent method with antibodies to Α-smooth muscle actin and desmin. HESMC are negative for HIV-1, HBV, HCV, mycoplasma, bacteria, yeast and fungi. HESMC are guaranteed to further expand for 15 population doublings at the condition provided by AcceGen Research Laboratories.

Disease

Normal

Source Organ

Esophagus

Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Recommended Medium And Supplement
Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Application

For research use only

Growth Conditions

37 ℃, 5% CO2

Cell Type

Smooth Muscle Cell

Growth Mode

Adherent

Product Type

Esophageal Cells

Product Image AcceGen Frozen Cells & Cell Lines 1 vial
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