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Human Esophageal Epithelial Cells

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Human Esophageal Epithelial Cells

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1 vial

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Dry Ice


Liquid Nitrogen


Human esophageal epithelial cells are separated from the esophagus, which is a hollow tubular organ cosisting of mucosa or epithelium, submucosa, muscle, and adventitia. The stratified squamous esophageal epithelium serves as a barrier that prevents mechanical and chemical damage caused by food stream. The esophageal epithelium has three compartments: a proliferating basal cell compartment, a differentiating suprabasal cell compartment, and a superficial squamous cell compartment. The basal cells of esophageal epithelium express cytokeratins 5 and 14 (CK5, CK14). The suprabasal layer expresses CK4 and CK17. Filaggrin and involucrin are found in the superficial cell layer of the esophagus. Different from murine esophageal epithelium, human esophageal epithelium is non-keratinized with the retained cell nucleus.


Why choose Human Esophageal Epithelial Cells from AcceGen?

AcceGen supports the cell product for human esophageal epithelial cells at more than 5×105 cells in 1 mL volume with the best viability and plating efficiency. Every customer is provided with the information for storage and handling on the product website. We have strict test procedures for product quality and reliability control. Human esophageal epithelial cells were tested negative for mycoplasma, bacteria, yeast, fungi, HIV-1, HBV, and HCV. We guarantee that our cells can be further expanded for at least 15 population doublings in the condition provided by AcceGen Research Laboratory.



Source Organ


Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

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Citation Guide

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).



Human esophageal epithelial cells can be applied to investigate gene expression involved in the the formation of adherent junctions and tight junctions. Using human esophageal epithelial cells as a platform, it was found that loss of E-cadherin resulted in enhanced migration and invasion of esophageal epithelial cells. Moreover, overexpression of epidermal growth factor receptor (EGFR) can induce epithelial hyperplasia and increase thickness of epithelium. The expansion of the proliferating basal cells and impaired differentiation can be observed with the expression of inducible AKT in human esophageal epithelial cells. Otherwise, Esophageal squamous cell carcinoma (ESCC) is one of the most common and serious malignancies. Esophageal epithelial cell lines were used to identified potential biomarkers for ESCC, such as p53, Orai1, GPX3, REPS2, esophagin, proliferating cell nuclear antigen (PCNA), epithelial cell transforming sequence 2 (ECT2), etc.

Growth Conditions

37 ℃, 5% CO2

Cell Type


Growth Mode


Product Type

Esophageal Cells

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