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Transfected Stable Cell Lines

Human FGFR2 (L617V) BICC1 BAF3 Cell Line

  • For research use only

Cat No.

ABC-X0192C
Product Type

Overexpression Stable Cell Lines
Cell Type

Lymphocytes
Species

Human
Host Cell

BAF3
Source Organ

Lymphatic
Disease

Normal
Storage

Liquid Nitrogen

The human FGFR2 (L617V) BICC1 BAF3 Cell Line provides a model for FGFR2-altered tumor biology and facilitates screening of FGFR-targeted inhibitors.

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  • Human FGFR2 (L617V) BICC1 BAF3 Cell Line
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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2 (L617V) BICC1 BAF3 Cell Line

Description

Human FGFR2 (L617V) BICC1 BAF3 Cell Line is a stable Ba/F3-derived model expressing the FGFR2-BICC1 fusion with the L617V point mutation. Lentiviral transduction ensures durable expression, verified by qRT-PCR. Low passage numbers (<P20) are maintained. Target The FGFR2-BICC1 fusion is an oncogenic driver in biliary tract cancers. The L617V mutation lies within the kinase domain and may influence inhibitor binding and downstream signaling fidelity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

Species

Human
Cat.No

ABC-X0192C
Product Category

Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Growth Mode

Suspension
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.

Application

  • This cell line is suitable for kinase domain mutation functional assays, FGFR inhibitor profiling, and oncogenic pathway mapping.

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High Viability
To succeed in cell culture
Precision and Reliability
To support a consistent result
Customization Options
Tailed to your research

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