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Human FGFR2 (L617V) BICC1 BAF3 Cell Line

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Home | Transfected Stable Cell Lines | Overexpression Stable Cell Lines | Human FGFR2 (L617V) BICC1 BAF3 Cell Line
Species

Human
Cat.No

ABC-X0192C
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Transfected Stable Cell Lines
Size/Quantity

1 vial
Cell Type

Lymphocytes
Shipping Info

Dry Ice
Growth Conditions

37 °C, 5% CO2
Source Organ

Lymphatic
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Overexpression Stable Cell Lines
Host Cell

BAF3

Description

Human FGFR2 (L617V) BICC1 BAF3 Cell Line is a stable Ba/F3-derived model expressing the FGFR2-BICC1 fusion with the L617V point mutation. Lentiviral transduction ensures durable expression, verified by qRT-PCR. Low passage numbers (<P20) are maintained. Target The FGFR2-BICC1 fusion is an oncogenic driver in biliary tract cancers. The L617V mutation lies within the kinase domain and may influence inhibitor binding and downstream signaling fidelity. AcceGen offers generation of stable overexpression cell lines targeting any gene of your interest. Polyclonal or monoclonal is optional based on customers' research needs.

AcceGen Frozen Cells & Cell Lines 1 vial
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Application

  • For research use only

  • This cell line is suitable for kinase domain mutation functional assays, FGFR inhibitor profiling, and oncogenic pathway mapping.

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