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Primary Cells

Human Gingival Fibroblasts

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Fibroblasts are mesenchymal cells with many vital functions during development and in adult organisms. They are responsible for much of the synthesis of extracellular matrix in connective tissues and play major roles in wound healing. Many diseases are associated with fibroblasts, either because fibroblasts are implicated in their etiology or because of the fibrosis that […]
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Home | Primary Cells | Human Primary Cells | Digestive System Primary Cells | Human Gingival Fibroblasts
Product Code

HGnF
Species

Human
Cat.No

ABC-TC3627
Quality Control

All cells test negative for mycoplasma, bacteria, yeast, and fungi.
Product Category Primary Cells
Size/Quantity

1 vial
Cell Type

Fibroblast
Shipping Info

Dry Ice
Growth Conditions

37 ℃, 5% CO2
Source Organ

Gingival
Disease

Normal
Biosafety Level

1
Storage

Liquid Nitrogen
Product Type

Oral Cells
Key Features

-Backed by AcceGen advanced technology
-Cryopreserved for highest viability and plating efficiency
-Quality-tested for accurate results

Description

Gingival Fibroblasts (GF) are the most abundant cell types found in gingival connective tissue. The key function of gingival fibroblast is to synthesis and maintain extracellular matric (ECM) and repair tissue upon oral damage. Human gingival fibroblasts also play a key role in sustaining inflammation response by interacting with pathogens and their component lipopolysaccharide (LPS) in periodontal disease. Due to its accessibility, superior wound closure rate, and low donor site morbidity compared to fibroblasts in other tissues, gingival fibroblast culture represents an ideal source for in vitro periodontal study and good substitute for mesenchymal stem cells (MSCs).
Why Choose Human Gingival Fibroblasts from AcceGen
AcceGen Human Gingival Fibroblasts are isolated from human gingiva tissue following standardized protocols. Cells are cryopreserved at passage 2 with each vial containing more than 5×10^5 cells in 1 ml volume. Human gingival fibroblasts are not detected with HIV-1, HBV, HCV and other pathogens. Cells are characterized with expression of fibronectin by immunofluorescence. Human gingival fibroblasts are quality tested for further expansion of 15 population doublings with stable activity and morphology in AcceGen culture media.

AcceGen Frozen Cells & Cell Lines 1 vial
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Citation

When you publish your research, please cite our product as “AcceGen Biotech Cat.# XXX-0000”. In return, we’ll give you a $100 coupon. Simply click here and submit your paper’s PubMed ID (PMID).

Duru Aras-Tosun, Canan Önder, Nihan Akdoğan, Şivge Kurgan, İrem Aktay, Erkan Tuncay, Kaan Orhan, “Astaxanthin Enhances Gingival Wound Healing following High Glucose-Induced Oxidative Stress”, BioMed Research International, vol. 2022, Article ID 4043105, 7 pages, 2022. https://doi.org/10.1155/2022/4043105

Application

  • For research use only

  • Human Gingival Fibroblasts Applications
  • -Pathogenies of inflammatory periodontal disease research
  • -Cell expression pattern and biophysiological characteristics associated with fibroblasts and periodontal disease
  • -Cytotoxicity assessment of drugs and fluoride varnishes used in dental practice
  • -Stem cell research and periodontal tissue engineering

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